Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes

Tumor hypoxia is a pathophysiologic outcome of disrupted microcirculation with inadequate supply of oxygen, leading to enhanced proliferation, epithelial-mesenchymal transition (EMT), metastasis, and chemo-resistance. Epigenetic changes induced by hypoxia are well documented, and they lead to tumor...

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Detalles Bibliográficos
Autores principales: Kao, Shih-Han, Wu, Kou-Juey, Lee, Wen-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773780/
https://www.ncbi.nlm.nih.gov/pubmed/26861406
http://dx.doi.org/10.3390/jcm5020024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773780/
https://www.ncbi.nlm.nih.gov/pubmed/26861406
http://dx.doi.org/10.3390/jcm5020024

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