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Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes

Tumor hypoxia is a pathophysiologic outcome of disrupted microcirculation with inadequate supply of oxygen, leading to enhanced proliferation, epithelial-mesenchymal transition (EMT), metastasis, and chemo-resistance. Epigenetic changes induced by hypoxia are well documented, and they lead to tumor...

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Detalles Bibliográficos
Autores principales:	Kao, Shih-Han, Wu, Kou-Juey, Lee, Wen-Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773780/ https://www.ncbi.nlm.nih.gov/pubmed/26861406 http://dx.doi.org/10.3390/jcm5020024

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