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A new approach to chemotherapy: drug-induced differentiation kills African trypanosomes

Human African trypanosomiasis (sleeping sickness) is a neglected tropical disease caused by Trypanosoma brucei spp. The parasites are transmitted by tsetse flies and adapt to their different hosts and environments by undergoing a series of developmental changes. During differentiation, the trypanoso...

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Detalles Bibliográficos
Autores principales: Wenzler, Tanja, Schumann Burkard, Gabriela, S. Schmidt, Remo, Mäser, Pascal, Bergner, Andreas, Roditi, Isabel, Brun, Reto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773815/
https://www.ncbi.nlm.nih.gov/pubmed/26931380
http://dx.doi.org/10.1038/srep22451