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Tumor-induced remote ECM network orientation steers angiogenesis

Tumor angiogenesis promotes tumor growth and metastasis. Here, we use automated sequential microprinting of tumor and endothelial cells in extracellular matrix (ECM) scaffolds to study its mechanical aspects. Quantitative reflection microscopy shows that tumor spheroids induce radial orientation of...

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Detalles Bibliográficos
Autores principales: Balcioglu, Hayri E., van de Water, Bob, Danen, Erik H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773852/
https://www.ncbi.nlm.nih.gov/pubmed/26931404
http://dx.doi.org/10.1038/srep22580