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MiR-708 promotes steroid-induced osteonecrosis of femoral head, suppresses osteogenic differentiation by targeting SMAD3

Steroid-induced osteonecrosis of femoral head (ONFH) is a serious complication of glucocorticoid (GC) use. We investigated the differential expression of miRs in the mesenchymal stem cells (MSCs) of patients with ONFH, and aimed to explain the relationship between GC use and the development of MSC d...

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Detalles Bibliográficos
Autores principales: Hao, Cheng, Yang, Shuhua, Xu, Weihua, Shen, Jacson K., Ye, Shunan, Liu, Xianzhe, Dong, Zhe, Xiao, Baojun, Feng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773864/
https://www.ncbi.nlm.nih.gov/pubmed/26932538
http://dx.doi.org/10.1038/srep22599