Intralymphatic mRNA vaccine induces CD8 T-cell responses that inhibit the growth of mucosally located tumours

The lack of appropriate mouse models is likely one of the reasons of a limited translational success rate of therapeutic vaccines against cervical cancer, as rapidly growing ectopic tumours are commonly used for preclinical studies. In this work, we demonstrate that the tumour microenvironment of TC...

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Detalles Bibliográficos
Autores principales: Bialkowski, Lukasz, van Weijnen, Alexia, Van der Jeught, Kevin, Renmans, Dries, Daszkiewicz, Lidia, Heirman, Carlo, Stangé, Geert, Breckpot, Karine, Aerts, Joeri L., Thielemans, Kris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773884/
https://www.ncbi.nlm.nih.gov/pubmed/26931556
http://dx.doi.org/10.1038/srep22509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773884/
https://www.ncbi.nlm.nih.gov/pubmed/26931556
http://dx.doi.org/10.1038/srep22509

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