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HSA: integrating multi-track Hi-C data for genome-scale reconstruction of 3D chromatin structure

Genome-wide 3C technologies (Hi-C) are being increasingly employed to study three-dimensional (3D) genome conformations. Existing computational approaches are unable to integrate accumulating data to facilitate studying 3D chromatin structure and function. We present HSA (http://ouyanglab.jax.org/hs...

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Detalles Bibliográficos
Autores principales: Zou, Chenchen, Zhang, Yuping, Ouyang, Zhengqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774023/
https://www.ncbi.nlm.nih.gov/pubmed/26936376
http://dx.doi.org/10.1186/s13059-016-0896-1