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Opposing presynaptic roles of BDNF and ProBDNF in the regulation of persistent activity in the entorhinal cortex
BACKGROUND: Sustained, persistent firing (PF) of cortical pyramidal neurons following a short depolarization is a crucial cellular mechanism required for spatial and working memory. Pyramidal neurons in the superficial and deep layers of the medial and lateral entorhinal cortex (EC) display this pro...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774087/ https://www.ncbi.nlm.nih.gov/pubmed/26932787 http://dx.doi.org/10.1186/s13041-016-0203-9 |