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Diagnostic and prognostic value of SHOX2 and SEPT9 DNA methylation and cytology in benign, paramalignant, and malignant ascites

BACKGROUND: Cytology remains the gold standard for the detection of malignant cells in ascites. However, its sensitivity is limited. The aim of this study was to evaluate DNA methylation biomarkers for the differential diagnosis of benign (ascites in patients without malignancy), malignant (ascites...

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Detalles Bibliográficos
Autores principales: Jung, Maria, Pützer, Svenja, Gevensleben, Heidrun, Meller, Sebastian, Kristiansen, Glen, Dietrich, Dimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774089/
https://www.ncbi.nlm.nih.gov/pubmed/26937257
http://dx.doi.org/10.1186/s13148-016-0192-7