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Anti-TNF certolizumab pegol induces antioxidant response in human monocytes via reverse signaling
BACKGROUND: Anti TNF drugs have been widely used in rheumatoid arthritis (RA) but only 70 to 80 % of patients respond to this therapy. Exploring the mode of action of anti-TNF drugs remains important in order to improve the efficiency of the treatment and enhance our knowledge of inflammation. TNF-α...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774095/ https://www.ncbi.nlm.nih.gov/pubmed/26932562 http://dx.doi.org/10.1186/s13075-016-0955-8 |