Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy

INTRODUCTION: The accumulation of insoluble proteins within neurons and glia cells is a pathological hallmark of several neurodegenerative diseases. Abnormal aggregation of the microtubule-associated protein tau characterizes the neuropathology of tauopathies, such as Alzheimer disease (AD), cortico...

Descripción completa

Detalles Bibliográficos
Autores principales: Piras, Antonio, Collin, Ludovic, Grüninger, Fiona, Graff, Caroline, Rönnbäck, Annica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774096/
https://www.ncbi.nlm.nih.gov/pubmed/26936765
http://dx.doi.org/10.1186/s40478-016-0292-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774096/
https://www.ncbi.nlm.nih.gov/pubmed/26936765
http://dx.doi.org/10.1186/s40478-016-0292-9

Ejemplares similares