Cargando…

Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy

INTRODUCTION: The accumulation of insoluble proteins within neurons and glia cells is a pathological hallmark of several neurodegenerative diseases. Abnormal aggregation of the microtubule-associated protein tau characterizes the neuropathology of tauopathies, such as Alzheimer disease (AD), cortico...

Descripción completa

Detalles Bibliográficos
Autores principales:	Piras, Antonio, Collin, Ludovic, Grüninger, Fiona, Graff, Caroline, Rönnbäck, Annica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774096/ https://www.ncbi.nlm.nih.gov/pubmed/26936765 http://dx.doi.org/10.1186/s40478-016-0292-9

Ejemplares similares

Case report of a patient with unclassified tauopathy with molecular and neuropathological features of both progressive supranuclear palsy and corticobasal degeneration
por: Koga, Shunsuke, et al.
Publicado: (2023)

Progressive Supranuclear Palsy and Corticobasal Degeneration: Pathophysiology and Treatment Options
por: Lamb, Ruth, et al.
Publicado: (2016)

Progressive supranuclear palsy and corticobasal degeneration: novel clinical concepts and advances in biomarkers
por: Parmera, Jacy Bezerra, et al.
Publicado: (2022)

Contribution of the astrocytic tau pathology to synapse loss in progressive supranuclear palsy and corticobasal degeneration
por: Briel, Nils, et al.
Publicado: (2020)

Language impairment in progressive supranuclear palsy and corticobasal syndrome
por: Peterson, Katie A., et al.
Publicado: (2019)

Caregiver strain in progressive supranuclear palsy and corticobasal syndromes
por: Kellermair, Lukas, et al.
Publicado: (2021)

Associations of mitochondrial genomic variation with corticobasal degeneration, progressive supranuclear palsy, and neuropathological tau measures
por: Valentino, Rebecca R., et al.
Publicado: (2020)

A Case of Pathologically Confirmed Corticobasal Degeneration Initially Presenting as Progressive Supranuclear Palsy Syndrome
por: Chung, Eun Joo, et al.
Publicado: (2022)

Machine learning‐based decision tree classifier for the diagnosis of progressive supranuclear palsy and corticobasal degeneration
por: Koga, Shunsuke, et al.
Publicado: (2021)

Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome
por: Jabbari, Edwin, et al.
Publicado: (2020)

Cerebellar contributions to cognition in corticobasal syndrome and progressive supranuclear palsy
por: Tse, Nga Yan, et al.
Publicado: (2020)

Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy
por: Kouri, Naomi, et al.
Publicado: (2015)

MAPT ‐Associated Familial Progressive Supranuclear Palsy with Typical Corticobasal Degeneration Neuropathology: A Clinicopathological Report
por: Cullinane, Patrick W., et al.
Publicado: (2023)

Systematic Review of Prevalence Studies of Progressive Supranuclear Palsy and Corticobasal Syndrome
por: Swallow, Diane M.A., et al.
Publicado: (2022)

Progression of Microstructural Degeneration in Progressive Supranuclear Palsy and Corticobasal Syndrome: A Longitudinal Diffusion Tensor Imaging Study
por: Zhang, Yu, et al.
Publicado: (2016)

Distinct subcortical tau burden: The tau pallido‐claustral ratio separates progressive supranuclear palsy and corticobasal degeneration
por: Zhao, Chelsey ShengQi, et al.
Publicado: (2021)

Single-nucleus chromatin accessibility profiling highlights distinct astrocyte signatures in progressive supranuclear palsy and corticobasal degeneration
por: Briel, Nils, et al.
Publicado: (2022)

Characteristics of progressive supranuclear palsy presenting with corticobasal syndrome: a cortical variant
por: Ling, H, et al.
Publicado: (2014)

Abnormal Resting-State Functional Connectivity in Progressive Supranuclear Palsy and Corticobasal Syndrome
por: Bharti, Komal, et al.
Publicado: (2017)

The clinico-metabolic correlates of language impairment in corticobasal syndrome and progressive supranuclear palsy
por: Dodich, Alessandra, et al.
Publicado: (2019)

Network connectivity and structural correlates of survival in progressive supranuclear palsy and corticobasal syndrome
por: Whiteside, David J., et al.
Publicado: (2023)

Diagnostic Accuracy of Magnetic Resonance Imaging Measures of Brain Atrophy Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Degeneration
por: Illán-Gala, Ignacio, et al.
Publicado: (2022)

Migraine and Tension-type Headache in Parkinson's Disease and Progressive Supranuclear Palsy/Corticobasal Syndrome
por: Jatale, Vinayak, et al.
Publicado: (2023)

Identification of common variants influencing risk of the tauopathy Progressive Supranuclear Palsy
por: Höglinger, Günter U., et al.
Publicado: (2011)

The prevalence and incidence of progressive supranuclear palsy and corticobasal syndrome: a systematic review and meta-analysis
por: Lyons, Shane, et al.
Publicado: (2023)

Fiber-specific micro- and macroscopic white matter alterations in progressive supranuclear palsy and corticobasal syndrome
por: Uchida, Wataru, et al.
Publicado: (2023)

Tau pathology in aged cynomolgus monkeys is progressive supranuclear palsy/corticobasal degeneration- but not Alzheimer disease-like -Ultrastructural mapping of tau by EDX-
por: Uchihara, Toshiki, et al.
Publicado: (2016)

Clinical Routine FDG-PET Imaging of Suspected Progressive Supranuclear Palsy and Corticobasal Degeneration: A Gatekeeper for Subsequent Tau-PET Imaging?
por: Beyer, Leonie, et al.
Publicado: (2018)

The evolution of diagnosis from symptom onset to death in progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) compared to Parkinson’s disease (PD)
por: Swallow, Diane M. A., et al.
Publicado: (2023)

Towards accurate and unbiased imaging-based differentiation of Parkinson’s disease, progressive supranuclear palsy and corticobasal syndrome
por: Correia, Marta M, et al.
Publicado: (2020)

Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool
por: Peterson, Katie A., et al.
Publicado: (2021)

Additive value of [(18)F]PI-2620 perfusion imaging in progressive supranuclear palsy and corticobasal syndrome
por: Katzdobler, Sabrina, et al.
Publicado: (2022)

Discriminative binding of tau PET tracers PI2620, MK6240 and RO948 in Alzheimer’s disease, corticobasal degeneration and progressive supranuclear palsy brains
por: Malarte, Mona-Lisa, et al.
Publicado: (2022)

Presence of Skin α-Synuclein Deposits Discriminates Parkinson’s Disease from Progressive Supranuclear Palsy and Corticobasal Syndrome
por: Giannoccaro, Maria Pia, et al.
Publicado: (2022)

Corticobasal degeneration and corticobasal syndrome: A review
por: Constantinides, Vasilios C., et al.
Publicado: (2019)

Interpretable Classification of Tauopathies with a Convolutional Neural Network Pipeline Using Transfer Learning and Validation against Post-Mortem Clinical Cases of Alzheimer’s Disease and Progressive Supranuclear Palsy
por: Diaz-Gomez, Liliana, et al.
Publicado: (2022)

The Small Heat Shock Protein HSP25/27 (HspB1) Is Abundant in Cultured Astrocytes and Associated with Astrocytic Pathology in Progressive Supranuclear Palsy and Corticobasal Degeneration
por: Schwarz, Lisa, et al.
Publicado: (2010)

PET Tau Imaging and Motor Impairments Differ Between Corticobasal Syndrome and Progressive Supranuclear Palsy With and Without Alzheimer's Disease Biomarkers
por: Vasilevskaya, Anna, et al.
Publicado: (2020)

The Rate of Decrease in Brain Perfusion in Progressive Supranuclear Palsy and Corticobasal Syndrome May Be Impacted by Glycemic Variability—A Pilot Study
por: Alster, Piotr, et al.
Publicado: (2021)

Best Practices in the Clinical Management of Progressive Supranuclear Palsy and Corticobasal Syndrome: A Consensus Statement of the CurePSP Centers of Care
por: Bluett, Brent, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4neeitqm43esb06thbobiqh3tn