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Systematic analysis of overall survival and interactions between tumor mutations and drug treatment

BACKGROUND: Few exceptional responses in cancer treatment were attributed to a genetic predisposition of the tumor. METHODS: We analyzed a cohort of 3105 patients from 12 different cancer types and systematically sought the existence of a correlation between overall survival and the interaction of 2...

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Detalles Bibliográficos
Autores principales: Gatto, Francesco, Nielsen, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774108/
https://www.ncbi.nlm.nih.gov/pubmed/26936071
http://dx.doi.org/10.1186/s13045-016-0249-2