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Improvement in glycemia after glucose or insulin overload in leptin-infused rats is associated with insulin-related activation of hepatic glucose metabolism

BACKGROUND: Insulin regulates glucose homeostasis through direct effects on the liver, among other organs, with leptin modulating insulin’s hepatic actions. Since central leptin may modify insulin signaling in the liver, we hypothesized that leptin infusion activates hepatic glycogen synthesis follo...

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Detalles Bibliográficos
Autores principales: Burgos-Ramos, Emma, Canelles, Sandra, Frago, Laura M., Chowen, Julie A., Arilla-Ferreiro, Eduardo, Argente, Jesús, Barrios, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774133/
https://www.ncbi.nlm.nih.gov/pubmed/26937247
http://dx.doi.org/10.1186/s12986-016-0079-9