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Regulation of mTORC1 by growth factors, energy status, amino acids and mechanical stimuli at a glance
The mechanistic/mammalian target of rapamycin complex 1 (mTORC1) plays a pivotal role in the regulation of skeletal muscle protein synthesis. Activation of the complex leads to phosphorylation of two important sets of substrates, namely eIF4E binding proteins and ribosomal S6 kinases. Phosphorylatio...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774173/ https://www.ncbi.nlm.nih.gov/pubmed/26937223 http://dx.doi.org/10.1186/s12970-016-0118-y |