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IL-27 inhibits the TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells
BACKGROUND: IL-27 is a multifunctional cytokine that has both pro-inflammatory and anti-inflammatory functions. Although IL-27 has been shown to potently inhibit lung fibrosis, the detailed mechanism of IL-27 in this process is poorly understood. Epithelial–mesenchymal transition (EMT) is one of the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774182/ https://www.ncbi.nlm.nih.gov/pubmed/26932661 http://dx.doi.org/10.1186/s12860-016-0084-x |