The relative importance of kinetic mechanisms and variable enzyme abundances for the regulation of hepatic glucose metabolism – insights from mathematical modeling

BACKGROUND: Adaptation of the cellular metabolism to varying external conditions is brought about by regulated changes in the activity of enzymes and transporters. Hormone-dependent reversible enzyme phosphorylation and concentration changes of reactants and allosteric effectors are the major types...

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Detalles Bibliográficos
Autores principales: Bulik, Sascha, Holzhütter, Hermann-Georg, Berndt, Nikolaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774192/
https://www.ncbi.nlm.nih.gov/pubmed/26935066
http://dx.doi.org/10.1186/s12915-016-0237-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774192/
https://www.ncbi.nlm.nih.gov/pubmed/26935066
http://dx.doi.org/10.1186/s12915-016-0237-6

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