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Rapamycin prevents acute dendritic injury following seizures

OBJECTIVE: Seizures cause acute structural changes in dendrites, which may contribute to cognitive deficits that occur in epilepsy patients. Disruption of the actin cytoskeleton of dendrites likely mediates the structural changes following seizures, but the upstream signaling mechanisms activated by...

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Detalles Bibliográficos
Autores principales: Guo, Dongjun, Zeng, Linghui, Zou, Jia, Chen, Linglin, Rensing, Nicholas, Wong, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774262/
https://www.ncbi.nlm.nih.gov/pubmed/27042678
http://dx.doi.org/10.1002/acn3.284