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Structural and Functional Characterization of a Single-Chain Form of the Recognition Domain of Complement Protein C1q

Complement C1q is a soluble pattern recognition molecule comprising six heterotrimeric subunits assembled from three polypeptide chains (A–C). Each heterotrimer forms a collagen-like stem prolonged by a globular recognition domain. These recognition domains sense a wide variety of ligands, including...

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Detalles Bibliográficos
Autores principales: Moreau, Christophe, Bally, Isabelle, Chouquet, Anne, Bottazzi, Barbara, Ghebrehiwet, Berhane, Gaboriaud, Christine, Thielens, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774423/
https://www.ncbi.nlm.nih.gov/pubmed/26973654
http://dx.doi.org/10.3389/fimmu.2016.00079