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Structural and Functional Characterization of a Single-Chain Form of the Recognition Domain of Complement Protein C1q
Complement C1q is a soluble pattern recognition molecule comprising six heterotrimeric subunits assembled from three polypeptide chains (A–C). Each heterotrimer forms a collagen-like stem prolonged by a globular recognition domain. These recognition domains sense a wide variety of ligands, including...
Autores principales: | Moreau, Christophe, Bally, Isabelle, Chouquet, Anne, Bottazzi, Barbara, Ghebrehiwet, Berhane, Gaboriaud, Christine, Thielens, Nicole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774423/ https://www.ncbi.nlm.nih.gov/pubmed/26973654 http://dx.doi.org/10.3389/fimmu.2016.00079 |
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