iRhoms; Its Functions and Essential Roles

In Drosophila, rhomboid proteases are active cardinal regulators of epidermal growth factor receptor (EGFR) signaling pathway. iRhom1 and iRhom2, which are inactive homologs of rhomboid intramembrane serine proteases, are lacking essential catalytic residues. These are necessary for maturation and t...

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Detalles Bibliográficos
Autores principales: Lee, Min-Young, Nam, Ki-Hoan, Choi, Kyung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774490/
https://www.ncbi.nlm.nih.gov/pubmed/26869525
http://dx.doi.org/10.4062/biomolther.2015.149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774490/
https://www.ncbi.nlm.nih.gov/pubmed/26869525
http://dx.doi.org/10.4062/biomolther.2015.149

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