Assessment of the Cytotoxic and Apoptotic Effects of Chaetominine in a Human Leukemia Cell Line

Chaetominine is a quinazoline alkaloid originating from the endophytic fungus Aspergillus fumigatus CY018. In this study, we showed evidence that chaetominine has cytotoxic and apoptotic effects on human leukemia K562 cells and investigated the pathway involved in chaetominine-induced apoptosis in d...

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Detalles Bibliográficos
Autores principales: Yao, Jingyun, Jiao, Ruihua, Liu, Changqing, Zhang, Yupeng, Yu, Wanguo, Lu, Yanhua, Tan, Renxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774495/
https://www.ncbi.nlm.nih.gov/pubmed/26902083
http://dx.doi.org/10.4062/biomolther.2015.093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774495/
https://www.ncbi.nlm.nih.gov/pubmed/26902083
http://dx.doi.org/10.4062/biomolther.2015.093

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