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Reactivation of Latent HIV-1 Expression by Engineered TALE Transcription Factors
The presence of replication-competent HIV-1 –which resides mainly in resting CD4(+) T cells–is a major hurdle to its eradication. While pharmacological approaches have been useful for inducing the expression of this latent population of virus, they have been unable to purge HIV-1 from all its reserv...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774903/ https://www.ncbi.nlm.nih.gov/pubmed/26933881 http://dx.doi.org/10.1371/journal.pone.0150037 |