Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds

In 2010 the identities of thousands of anti-Plasmodium compounds were released publicly to facilitate malaria drug development. Understanding these compounds’ mechanisms of action—i.e., the specific molecular targets by which they kill the parasite—would further facilitate the drug development proce...

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Detalles Bibliográficos
Autores principales: Crowther, Gregory J., Hillesland, Heidi K., Keyloun, Katelyn R., Reid, Molly C., Lafuente-Monasterio, Maria Jose, Ghidelli-Disse, Sonja, Leonard, Stephen E., He, Panqing, Jones, Jackson C., Krahn, Mallory M., Mo, Jack S., Dasari, Kartheek S., Fox, Anna M. W., Boesche, Markus, El Bakkouri, Majida, Rivas, Kasey L., Leroy, Didier, Hui, Raymond, Drewes, Gerard, Maly, Dustin J., Van Voorhis, Wesley C., Ojo, Kayode K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774911/
https://www.ncbi.nlm.nih.gov/pubmed/26934697
http://dx.doi.org/10.1371/journal.pone.0149996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774911/
https://www.ncbi.nlm.nih.gov/pubmed/26934697
http://dx.doi.org/10.1371/journal.pone.0149996

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