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CpG Improves Influenza Vaccine Efficacy in Young Adult but Not Aged Mice

Several studies have shown a reduced efficacy of influenza vaccines in the elderly compared to young adults. In this study, we evaluated the immunogenicity and protective efficacy of a commercially available inactivated influenza vaccine (Fluzone(®)) in young adult and aged mice. C57/BL6 mice were a...

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Detalles Bibliográficos
Autores principales: Ramirez, Alejandro, Co, Mary, Mathew, Anuja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774967/
https://www.ncbi.nlm.nih.gov/pubmed/26934728
http://dx.doi.org/10.1371/journal.pone.0150425