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Mechanism of Copper Uptake from Blood Plasma Ceruloplasmin by Mammalian Cells

Ceruloplasmin, the main copper binding protein in blood plasma, has been of particular interest for its role in efflux of iron from cells, but has additional functions. Here we tested the hypothesis that it releases its copper for cell uptake by interacting with a cell surface reductase and transpor...

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Detalles Bibliográficos
Autores principales: Ramos, Danny, Mar, David, Ishida, Michael, Vargas, Rebecca, Gaite, Michaella, Montgomery, Aaron, Linder, Maria C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774968/
https://www.ncbi.nlm.nih.gov/pubmed/26934375
http://dx.doi.org/10.1371/journal.pone.0149516