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Human Monocyte-Derived Osteoclasts Are Targeted by Staphylococcal Pore-Forming Toxins and Superantigens

Staphylococcus aureus is the leading cause of bone and joint infections (BJIs). Staphylococcal pathogenesis involves numerous virulence factors including secreted toxins such as pore-forming toxins (PFTs) and superantigens. The role of these toxins on BJI outcome is largely unknown. In particular, f...

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Detalles Bibliográficos
Autores principales: Flammier, Sacha, Rasigade, Jean-Philippe, Badiou, Cédric, Henry, Thomas, Vandenesch, François, Laurent, Frédéric, Trouillet-Assant, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774977/
https://www.ncbi.nlm.nih.gov/pubmed/26934588
http://dx.doi.org/10.1371/journal.pone.0150693