Effects of UCP4 on the Proliferation and Apoptosis of Chondrocytes: Its Possible Involvement and Regulation in Osteoarthritis

Reactive oxygen species (ROS)-induced chondrocytes apoptosis plays a key role in osteoarthritis (OA) pathogenesis. Uncoupling protein 4 (UCP4) can protect cells against oxidative stress via reducing ROS production and cell apoptosis. Here, silencing of UCP4 in primary chondrocytes significantly inhi...

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Detalles Bibliográficos
Autores principales: Huang, Zhongming, Li, Junhua, Du, Shaohua, Chen, Guangnan, Qi, Yiying, Huang, Ligang, Xiao, Luwei, Tong, Peijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775028/
https://www.ncbi.nlm.nih.gov/pubmed/26934480
http://dx.doi.org/10.1371/journal.pone.0150684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775028/
https://www.ncbi.nlm.nih.gov/pubmed/26934480
http://dx.doi.org/10.1371/journal.pone.0150684

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