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Performance of Different Analytical Software Packages in Quantification of DNA Methylation by Pyrosequencing

BACKGROUND: Pyrosequencing has emerged as an alternative method of nucleic acid sequencing, well suited for many applications which aim to characterize single nucleotide polymorphisms, mutations, microbial types and CpG methylation in the target DNA. The commercially available pyrosequencing systems...

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Detalles Bibliográficos
Autores principales: Grasso, Chiara, Trevisan, Morena, Fiano, Valentina, Tarallo, Valentina, De Marco, Laura, Sacerdote, Carlotta, Richiardi, Lorenzo, Merletti, Franco, Gillio-Tos, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775062/
https://www.ncbi.nlm.nih.gov/pubmed/26934703
http://dx.doi.org/10.1371/journal.pone.0150483