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Performance of Different Analytical Software Packages in Quantification of DNA Methylation by Pyrosequencing
BACKGROUND: Pyrosequencing has emerged as an alternative method of nucleic acid sequencing, well suited for many applications which aim to characterize single nucleotide polymorphisms, mutations, microbial types and CpG methylation in the target DNA. The commercially available pyrosequencing systems...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775062/ https://www.ncbi.nlm.nih.gov/pubmed/26934703 http://dx.doi.org/10.1371/journal.pone.0150483 |