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Raised Intracellular Calcium Contributes to Ischemia-Induced Depression of Evoked Synaptic Transmission

Oxygen-glucose deprivation (OGD) leads to depression of evoked synaptic transmission, for which the mechanisms remain unclear. We hypothesized that increased presynaptic [Ca(2+)](i) during transient OGD contributes to the depression of evoked field excitatory postsynaptic potentials (fEPSPs). Additi...

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Detalles Bibliográficos
Autores principales: Jalini, Shirin, Ye, Hui, Tonkikh, Alexander A., Charlton, Milton P., Carlen, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775070/
https://www.ncbi.nlm.nih.gov/pubmed/26934214
http://dx.doi.org/10.1371/journal.pone.0148110