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The relative merits of therapies being developed to tackle inappropriate (‘self’-directed) complement activation
The complement system is an enzyme cascade that helps defend against infection. Many complement proteins occur in serum as inactive enzyme precursors or reside on cell surfaces. Complement components have many biologic functions and their activation can eventually damage the plasma membranes of cell...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775539/ https://www.ncbi.nlm.nih.gov/pubmed/26935316 http://dx.doi.org/10.1007/s13317-016-0078-x |