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Radiotherapy Suppresses Bone Cancer Pain through Inhibiting Activation of cAMP Signaling in Rat Dorsal Root Ganglion and Spinal Cord

Radiotherapy is one of the major clinical approaches for treatment of bone cancer pain. Activation of cAMP-PKA signaling pathway plays important roles in bone cancer pain. Here, we examined the effects of radiotherapy on bone cancer pain and accompanying abnormal activation of cAMP-PKA signaling. Fe...

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Detalles Bibliográficos
Autores principales: Zhu, Guiqin, Dong, Yanbin, He, Xueming, Zhao, Ping, Yang, Aixing, Zhou, Rubing, Ma, Jianhua, Xie, Zhong, Song, Xue-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775803/
https://www.ncbi.nlm.nih.gov/pubmed/26989332
http://dx.doi.org/10.1155/2016/5093095