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Novel Bioluminescent Activatable Reporter for Src Tyrosine Kinase Activity in Living Mice
Aberrant activation of the Src kinase is implicated in the development of a variety of human malignancies. However, it is almost impossible to monitor Src activity in an in vivo setting with current biochemical techniques. To facilitate the noninvasive investigation of the activity of Src kinase bot...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775867/ https://www.ncbi.nlm.nih.gov/pubmed/26941850 http://dx.doi.org/10.7150/thno.14306 |