Potent Antiviral Activities of the Direct-Acting Antivirals ABT-493 and ABT-530 with Three-Day Monotherapy for Hepatitis C Virus Genotype 1 Infection

ABT-493 is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor, and ABT-530 is an HCV NS5A inhibitor. These direct-acting antivirals (DAAs) demonstrated potent antiviral activity against major HCV genotypes and high barriers to resistance in vitro. In this open-label dose-ra...

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Detalles Bibliográficos
Autores principales: Lawitz, Eric J., O'Riordan, William D., Asatryan, Armen, Freilich, Bradley L., Box, Terry D., Overcash, J. Scott, Lovell, Sandra, Ng, Teresa I., Liu, Wei, Campbell, Andrew, Lin, Chih-Wei, Yao, Betty, Kort, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775945/
https://www.ncbi.nlm.nih.gov/pubmed/26711747
http://dx.doi.org/10.1128/AAC.02264-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775945/
https://www.ncbi.nlm.nih.gov/pubmed/26711747
http://dx.doi.org/10.1128/AAC.02264-15

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