Repeated Blockade of NMDA Receptors During Adolescence Impairs Reversal Learning and Disrupts GABAergic Interneurons in Rat Medial Prefrontal Cortex

Adolescence is of particular significance to schizophrenia, since psychosis onset typically occurs in this critical period. Based on the N-methyl-D-aspartate (NMDA) receptor hypofunction hypothesis of schizophrenia, in this study, we investigated whether and how repeated NMDA receptor blockade durin...

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Detalles Bibliográficos
Autores principales: Li, Ji-Tao, Su, Yun-Ai, Wang, Hong-Li, Zhao, Ying-Ying, Liao, Xue-Mei, Wang, Xiao-Dong, Si, Tian-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776083/
https://www.ncbi.nlm.nih.gov/pubmed/26973457
http://dx.doi.org/10.3389/fnmol.2016.00017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776083/
https://www.ncbi.nlm.nih.gov/pubmed/26973457
http://dx.doi.org/10.3389/fnmol.2016.00017

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