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Repeated Blockade of NMDA Receptors During Adolescence Impairs Reversal Learning and Disrupts GABAergic Interneurons in Rat Medial Prefrontal Cortex
Adolescence is of particular significance to schizophrenia, since psychosis onset typically occurs in this critical period. Based on the N-methyl-D-aspartate (NMDA) receptor hypofunction hypothesis of schizophrenia, in this study, we investigated whether and how repeated NMDA receptor blockade durin...
Autores principales: | Li, Ji-Tao, Su, Yun-Ai, Wang, Hong-Li, Zhao, Ying-Ying, Liao, Xue-Mei, Wang, Xiao-Dong, Si, Tian-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776083/ https://www.ncbi.nlm.nih.gov/pubmed/26973457 http://dx.doi.org/10.3389/fnmol.2016.00017 |
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