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Distinct phosphorylation sites on the ghrelin receptor, GHSR1a, establish a code that determines the functions of ß-arrestins

The growth hormone secretagogue receptor, GHSR1a, mediates the biological activities of ghrelin, which includes the secretion of growth hormone, as well as the stimulation of appetite, food intake and maintenance of energy homeostasis. Mapping phosphorylation sites on GHSR1a and knowledge of how the...

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Detalles Bibliográficos
Autores principales: Bouzo-Lorenzo, Monica, Santo-Zas, Icía, Lodeiro, Maria, Nogueiras, Rubén, Casanueva, Felipe F., Castro, Marian, Pazos, Yolanda, Tobin, Andrew B, Butcher, Adrian J., Camiña, Jesús P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776146/
https://www.ncbi.nlm.nih.gov/pubmed/26935831
http://dx.doi.org/10.1038/srep22495