Cargando…

Deciphering DNA replication dynamics in eukaryotic cell populations in relation with their averaged chromatin conformations

We propose a non-local model of DNA replication that takes into account the observed uncertainty on the position and time of replication initiation in eukaryote cell populations. By picturing replication initiation as a two-state system and considering all possible transition configurations, and by...

Descripción completa

Detalles Bibliográficos
Autores principales: Goldar, A., Arneodo, A., Audit, B., Argoul, F., Rappailles, A., Guilbaud, G., Petryk, N., Kahli, M., Hyrien, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776152/
https://www.ncbi.nlm.nih.gov/pubmed/26935043
http://dx.doi.org/10.1038/srep22469