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Deciphering DNA replication dynamics in eukaryotic cell populations in relation with their averaged chromatin conformations
We propose a non-local model of DNA replication that takes into account the observed uncertainty on the position and time of replication initiation in eukaryote cell populations. By picturing replication initiation as a two-state system and considering all possible transition configurations, and by...
Autores principales: | Goldar, A., Arneodo, A., Audit, B., Argoul, F., Rappailles, A., Guilbaud, G., Petryk, N., Kahli, M., Hyrien, O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776152/ https://www.ncbi.nlm.nih.gov/pubmed/26935043 http://dx.doi.org/10.1038/srep22469 |
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