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Intracellular kinetics of the androgen receptor shown by multimodal Image Correlation Spectroscopy (mICS)

The androgen receptor (AR) pathway plays a central role in prostate cancer (PCa) growth and progression and is a validated therapeutic target. In response to ligand binding AR translocates to the nucleus, though the molecular mechanism is not well understood. We therefore developed multimodal Image...

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Detalles Bibliográficos
Autores principales: Chiu, Chi-Li, Patsch, Katherin, Cutrale, Francesco, Soundararajan, Anjana, Agus, David B., Fraser, Scott E., Ruderman, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776155/
https://www.ncbi.nlm.nih.gov/pubmed/26936218
http://dx.doi.org/10.1038/srep22435