Perinatal Exposure to Neuregulin-1 Results in Disinhibition of Adult Midbrain Dopaminergic Neurons: Implication in Schizophrenia Modeling

Aberrant neuregulin-1 (NRG1) signals are suggested to associate with the neuropathophysiology of schizophrenia. Employing a mouse schizophrenia model established by neonatal neuregulin-1 challenge, we analysed postpubertal consequence of the NRG1 pretreatment for the electrophysiological property of...

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Detalles Bibliográficos
Autores principales: Namba, Hisaaki, Okubo, Takeshi, Nawa, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776181/
https://www.ncbi.nlm.nih.gov/pubmed/26935991
http://dx.doi.org/10.1038/srep22606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776181/
https://www.ncbi.nlm.nih.gov/pubmed/26935991
http://dx.doi.org/10.1038/srep22606

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