Cargando…

Perinatal Exposure to Neuregulin-1 Results in Disinhibition of Adult Midbrain Dopaminergic Neurons: Implication in Schizophrenia Modeling

Aberrant neuregulin-1 (NRG1) signals are suggested to associate with the neuropathophysiology of schizophrenia. Employing a mouse schizophrenia model established by neonatal neuregulin-1 challenge, we analysed postpubertal consequence of the NRG1 pretreatment for the electrophysiological property of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Namba, Hisaaki, Okubo, Takeshi, Nawa, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776181/ https://www.ncbi.nlm.nih.gov/pubmed/26935991 http://dx.doi.org/10.1038/srep22606

Ejemplares similares

Neuropathologic Implication of Peripheral Neuregulin-1 and EGF Signals in Dopaminergic Dysfunction and Behavioral Deficits Relevant to Schizophrenia: Their Target Cells and Time Window
por: Nawa, Hiroyuki, et al.
Publicado: (2014)

Disinhibition Bursting of Dopaminergic Neurons
por: Lobb, Collin J., et al.
Publicado: (2011)

Overexpression of neuregulin 1 in GABAergic interneurons results in reversible cortical disinhibition
por: Wang, Yao-Yi, et al.
Publicado: (2021)

The generation of disinhibition bursts of dopaminergic neurons in the basal ganglia
por: Lobb, Collin J, et al.
Publicado: (2010)

Acquisition of the Midbrain Dopaminergic Neuronal Identity
por: Mesman, Simone, et al.
Publicado: (2020)

The Effects of Prenatal Exposure to Pregabalin on the Development of Ventral Midbrain Dopaminergic Neurons
por: Alsanie, Walaa F., et al.
Publicado: (2022)

Prenatal Exposure to Gabapentin Alters the Development of Ventral Midbrain Dopaminergic Neurons
por: Alsanie, Walaa F., et al.
Publicado: (2022)

The Influence of Prenatal Exposure to Methamphetamine on the Development of Dopaminergic Neurons in the Ventral Midbrain
por: Alsanie, Walaa F., et al.
Publicado: (2023)

Resting-state dopaminergic cell firing in the ventral tegmental area negatively regulates affiliative social interactions in a developmental animal model of schizophrenia
por: Sotoyama, Hidekazu, et al.
Publicado: (2021)

ErbB1-4-dependent EGF/neuregulin signals and their cross talk in the central nervous system: pathological implications in schizophrenia and Parkinson's disease
por: Iwakura, Yuriko, et al.
Publicado: (2013)

Schizophrenia Animal Modeling with Epidermal Growth Factor and Its Homologs: Their Connections to the Inflammatory Pathway and the Dopamine System
por: Sotoyama, Hidekazu, et al.
Publicado: (2023)

The immunogenicity of midbrain dopaminergic neurons and the implications for neural grafting trials in Parkinson’s disease
por: Qarin, Shamma, et al.
Publicado: (2021)

Dendritic involvement in inhibition and disinhibition of vulnerable dopaminergic neurons in healthy and pathological conditions
por: Evans, R.C.
Publicado: (2022)

Diverse midbrain dopaminergic neuron subtypes and implications for complex clinical symptoms of Parkinson’s disease
por: Carmichael, Kathleen, et al.
Publicado: (2021)

En1 and Wnt signaling in midbrain dopaminergic neuronal development
por: Alves dos Santos, Maria TM, et al.
Publicado: (2011)

Computational model of midbrain dopaminergic neuron activity in ageing and obesity
por: Popovych, Svitlana, et al.
Publicado: (2013)

Interaction of NMDA Receptor and Pacemaking Mechanisms in the Midbrain Dopaminergic Neuron
por: Ha, Joon, et al.
Publicado: (2013)

Cortical regulation of dopaminergic neurons: role of the midbrain superior colliculus
por: Bertram, C., et al.
Publicado: (2013)

Transcriptional comparison of human induced and primary midbrain dopaminergic neurons
por: Xia, Ninuo, et al.
Publicado: (2016)

Development and Differentiation of Midbrain Dopaminergic Neuron: From Bench to Bedside
por: Wang, Mengmeng, et al.
Publicado: (2020)

Efficient generation of dopaminergic induced neuronal cells with midbrain characteristics
por: Ng, Yi Han, et al.
Publicado: (2021)

The Influence of Prenatal Exposure to Quetiapine Fumarate on the Development of Dopaminergic Neurons in the Ventral Midbrain of Mouse Embryos
por: Alsanie, Walaa F., et al.
Publicado: (2022)

Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons
por: Tung, Li-Wei, et al.
Publicado: (2016)

Midbrain dopaminergic neuron fate specification: Of mice and embryonic stem cells
por: Gale, Emily, et al.
Publicado: (2008)

Social Modulation during Songbird Courtship Potentiates Midbrain Dopaminergic Neurons
por: Huang, Ya-Chun, et al.
Publicado: (2008)

An interlocked oscillator model for high-frequency firing of the midbrain dopaminergic neuron
por: Kuznetsov, Alexey, et al.
Publicado: (2011)

Calbindin content and differential vulnerability of midbrain efferent dopaminergic neurons in macaques
por: Dopeso-Reyes, Iria G., et al.
Publicado: (2014)

Neurotransmitter identity and electrophysiological phenotype are genetically coupled in midbrain dopaminergic neurons
por: Tapia, Mónica, et al.
Publicado: (2018)

Developmental pathways linked to the vulnerability of adult midbrain dopaminergic neurons to neurodegeneration
por: Prakash, Nilima
Publicado: (2022)

Efficient Generation of Dopaminergic Neurons from Mouse Ventral Midbrain Astrocytes
por: Han, Jin Yi, et al.
Publicado: (2023)

BACE1-Dependent Neuregulin-1 Signaling: An Implication for Schizophrenia
por: Zhang, Zhengrong, et al.
Publicado: (2017)

Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons
por: Iwakura, Yuriko, et al.
Publicado: (2017)

Calcitriol Imparts Neuroprotection In Vitro to Midbrain Dopaminergic Neurons by Upregulating GDNF Expression
por: Orme, Rowan P., et al.
Publicado: (2013)

Autophagic Impairment Contributes to Systemic Inflammation-Induced Dopaminergic Neuron Loss in the Midbrain
por: Zheng, Hui-Fen, et al.
Publicado: (2013)

Vesicular expression and release of ATP from dopaminergic neurons of the mouse retina and midbrain
por: Ho, Tracy, et al.
Publicado: (2015)

Midbrain Dopaminergic Neuron Development at the Single Cell Level: In vivo and in Stem Cells
por: Ásgrímsdóttir, Emilía Sif, et al.
Publicado: (2020)

Cryopreservation of Human Midbrain Dopaminergic Neural Progenitor Cells Poised for Neuronal Differentiation
por: Drummond, Nicola J., et al.
Publicado: (2020)

A protocol for the differentiation of human embryonic stem cells into midbrain dopaminergic neurons
por: Nishimura, Kaneyasu, et al.
Publicado: (2023)

Direct Glutamatergic Signaling From Midbrain Dopaminergic Neurons Onto Pyramidal Prefrontal Cortex Neurons
por: Pérez-López, José Luis, et al.
Publicado: (2018)

Investigating the effects of chronic perinatal alcohol and combined nicotine and alcohol exposure on dopaminergic and non-dopaminergic neurons in the VTA
por: Kazemi, Tina, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dr6nm715vfdtc9ucigbd0edkm7