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The Pathogenesis of Saffold Virus in AG129 Mice and the Effects of Its Truncated L Protein in the Central Nervous System

Saffold Virus (SAFV) is a human cardiovirus that has been suggested to cause severe infection of the central nervous system (CNS). Compared to a similar virus, Theiler’s murine encephalomyelitis virus (TMEV), SAFV has a truncated Leader (L) protein, a protein essential in the establishment of persis...

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Detalles Bibliográficos
Autores principales: Tan, Shawn Zheng Kai, Chua, Kaw Bing, Xu, Yishi, Prabakaran, Mookkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776182/
https://www.ncbi.nlm.nih.gov/pubmed/26901216
http://dx.doi.org/10.3390/v8020024