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Identification of Known and Novel Recurrent Viral Sequences in Data from Multiple Patients and Multiple Cancers

Virus discovery from high throughput sequencing data often follows a bottom-up approach where taxonomic annotation takes place prior to association to disease. Albeit effective in some cases, the approach fails to detect novel pathogens and remote variants not present in reference databases. We have...

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Detalles Bibliográficos
Autores principales: Friis-Nielsen, Jens, Kjartansdóttir, Kristín Rós, Mollerup, Sarah, Asplund, Maria, Mourier, Tobias, Jensen, Randi Holm, Hansen, Thomas Arn, Rey-Iglesia, Alba, Richter, Stine Raith, Nielsen, Ida Broman, Alquezar-Planas, David E., Olsen, Pernille V. S., Vinner, Lasse, Fridholm, Helena, Nielsen, Lars Peter, Willerslev, Eske, Sicheritz-Pontén, Thomas, Lund, Ole, Hansen, Anders Johannes, Izarzugaza, Jose M. G., Brunak, Søren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776208/
https://www.ncbi.nlm.nih.gov/pubmed/26907326
http://dx.doi.org/10.3390/v8020053