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A New Endogenous Overexpression System of Multidrug Transporters of Candida albicans Suitable for Structural and Functional Studies

Fungal pathogens have a robust array of multidrug transporters which aid in active expulsion of drugs and xenobiotics to help them evade toxic effects of drugs. Thus, these transporters impose a major impediment to effective chemotherapy. Although the Saccharomyces cerevisiae strain AD1-8u(−) has ca...

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Detalles Bibliográficos
Autores principales: Banerjee, Atanu, Khandelwal, Nitesh K., Sanglard, Dominique, Prasad, Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776216/
https://www.ncbi.nlm.nih.gov/pubmed/26973635
http://dx.doi.org/10.3389/fmicb.2016.00261