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A bead-based cleavage method for large-scale identification of protease substrates

Proteolysis is a major form of post translational modification which occurs when a protease cleaves peptide bonds in a target protein to modify its activity. Tracking protease substrates is indispensable for understanding its cellular functions. However, it is difficult to directly identify protease...

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Detalles Bibliográficos
Autores principales: Wang, Chunli, Ye, Mingliang, Wei, Xiaoluan, Bian, Yangyang, Cheng, Kai, Zou, Hanfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776233/
https://www.ncbi.nlm.nih.gov/pubmed/26935269
http://dx.doi.org/10.1038/srep22645