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Mapping Human Pluripotent-to-Cardiomyocyte Differentiation: Methylomes, Transcriptomes, and Exon DNA Methylation “Memories”

The directed differentiation of human cardiomyocytes (CMs) from pluripotent cells provides an invaluable model for understanding mechanisms of cell fate determination and offers considerable promise in cardiac regenerative medicine. Here, we utilize a human embryonic stem cell suspension bank, produ...

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Detalles Bibliográficos
Autores principales: Tompkins, Joshua D., Jung, Marc, Chen, Chang-yi, Lin, Ziguang, Ye, Jingjing, Godatha, Swetha, Lizhar, Elizabeth, Wu, Xiwei, Hsu, David, Couture, Larry A., Riggs, Arthur D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776252/
https://www.ncbi.nlm.nih.gov/pubmed/26981572
http://dx.doi.org/10.1016/j.ebiom.2016.01.021