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Mapping Human Pluripotent-to-Cardiomyocyte Differentiation: Methylomes, Transcriptomes, and Exon DNA Methylation “Memories”
The directed differentiation of human cardiomyocytes (CMs) from pluripotent cells provides an invaluable model for understanding mechanisms of cell fate determination and offers considerable promise in cardiac regenerative medicine. Here, we utilize a human embryonic stem cell suspension bank, produ...
Autores principales: | Tompkins, Joshua D., Jung, Marc, Chen, Chang-yi, Lin, Ziguang, Ye, Jingjing, Godatha, Swetha, Lizhar, Elizabeth, Wu, Xiwei, Hsu, David, Couture, Larry A., Riggs, Arthur D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776252/ https://www.ncbi.nlm.nih.gov/pubmed/26981572 http://dx.doi.org/10.1016/j.ebiom.2016.01.021 |
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