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Inhibition of cyclooxygenase-2 by NS398 attenuates noise-induced hearing loss in mice

Noise-induced hearing loss (NIHL) is an important occupational disorder. However, the molecular mechanisms underlying NIHL have not been fully clarified; therefore, the condition lacks effective therapeutic methods. Cyclooxygenase-2 (Cox-2) is an inducible enzyme involved in the synthesis of prostag...

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Detalles Bibliográficos
Autores principales: Sun, Yu, Yu, Jintao, Lin, Xi, Tang, Wenxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776277/
https://www.ncbi.nlm.nih.gov/pubmed/26934825
http://dx.doi.org/10.1038/srep22573